Rituximab as Rescue Therapy for Aggressive Pediatric Multiple Sclerosis

Multiple sclerosis is a chronic, debilitating disease.Almost one in ten patients with MS has a history of disease onset during childhood.Although numerous therapeutic Brownie Mix options exist for adult MS, the available treatments for pediatric patients are still limited.One of the emerging therapies is rituximab, a monoclonal anti-CD20 chimeric antibody that can deplete the CD20+ lymphocyte populations.A 12-year-old boy presented with ataxia, paresthesias, and headache while his brain MRI showed numerous T2 contrast-enhancing lesions.

Gamma globulin, steroids, and Building Blocks cyclophosphamide failed to intercept his disease, and he progressed to a rapid clinical and radiological deterioration.Treatment with rituximab reversed the disease course in a dramatic fashion, leading to complete remission.

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